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Words from Dr. Mario Nucci

“Ketamine inufsion is effective for treatment resistant depression in up to 70% of patients with repeat doses showing a cumulative benefit, Singh et al 2016. The antidepressant effects are rapid showing up within hours of treatment. ”


Kryst J, Kawalec P, Mitoraj AM, Pilc A, LasoĊ„ W, Brzostek T. Efficacy of single and repeated administration of ketamine in unipolar and bipolar depression: a meta-analysis of randomized clinical trials. Pharmacol Rep. 2020 Jun;72(3):543-562. doi: 10.1007/s43440-020-00097-z. Epub 2020 Apr 16. PMID: 32301056; PMCID: PMC7329804.

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